The BBC has asked Cardiff Council to build a 3,000 square-metre premises dedicated to the Doctor Who Experience in Porth Teigr.
The broadcaster plans to use the building to expand and "develop the Experience even further."
Once planning permission has been granted, details of the new Cardiff show will be revealed along with a closing date for the present Olympia location, where bookings can be made until November 20th.
The move will bring the attraction 'home', close to the BBC Cymru Wales studios where the drama is filmed.
Philip Murphy, managing director for live events at BBC Worldwide, commented: “We’ve worked very closely with Cardiff Council to bring the Experience to Cardiff, and we believe that it will draw fans to the Welsh capital from around the world."
The move has always been on the cards, with BBC Worldwide announcing its intention to shift the experience to Cardiff in September last year.
The Doctor Who Exhibition in Cardiff's Red Dragon Centre was recently closed in March. Aspects of that exhibit could resurface within the new attraction.
Keith Jones, director of BBC Cymru Wales, said: "Wales is the home of Doctor Who, our original made-in-Wales drama success story. Locating this fantastic experience in Cardiff Bay is a great development.”
In the TV show, Cardiff is home to a rift in time where The Doctor lands to refuel the Tardis.