Endemol is teaming up with Destination Software to create a video game for the Nintendo DS system based on the 1 vs 100 franchise.
This is the second collaboration for the two companies - they had previously worked together on a video game for Deal or No Deal.
The 1 vs 100 title will aim to recreate the TV quiz show: players can compete against a friend through a multiplayer challenge in a battle of brains, as one player must assume the role of 'The Mob' of 100 and stop the other from winning.
Other variations include a Poker-style trivia game, where players wager cash based on their confidence of the answer. The game will also feature the TV host Bob Saget.
"We strive to find unqiue ways to expand home entertainment and television viewership, and bringing a fantastic TV game show like 1 vs 100 to portable video gaming achieves those objectives," said Tina Hoover, director of production for Endemol USA.
"We look forward to continuing our relationship with DSI as they achieve repeated success with the family and casual gaming markets."