Fight My Monster will make a regular appearance in The Beano comic from Saturday, August 3rd.
The deal was struck between Lisle International and publishers DC Thomson.
Fight My Monster is a UK digital trading card game where online players battle each other to collect and trade cards. To play, fans simply log on to www.fightmymonster.com.
The popular children's brand is scheduled to appear in 13 issues of The Beano, which is celebrating its 75th birthday this year.
Francesca Lisle from Lisle International said: "The Beano is the perfect audience for Fight My Monster with a reach of over 420,000 readers in each of the 13 scheduled issues.
"We are therefore delighted to see the property take a regular presence in the comic. With this promotion, we hope to introduce even more users to the game each month and in so doing add further weight to the licensing programme."
A spokesperson for DC Thomson added: "We're delighted to be working with Fight My Monster. The Beano is the quintessential British children's comic and it makes hundreds of thousands of children laugh every week.
"Now in it's 75th year, The Beano is the longest running and one of the most successful comics in the world. That's because we continue to move with the times and represent what's going on in kids' lives today.
"Fight My Monster will bring a fantastic extra dimension to The Beno and we can't wait to discover the feedback from our readers."
Dominic Williams, CEO of Fight My Monster, said: "Fight My Monster has always blended humour with competition, and that makes The Beano an ideal partner.
"They have done a fantastic job bringing our characters to the comic format and are brilliant partners."
Fight My Monster is backed by various big names in the games and media industries including Greycroft Partners and eVenture Capital Partners.
The company has also recently revealed that it plans future expansion from web to mobile and tablet.
Want to receive up to the minute licensing industry news straight to your inbox? Click here to sign up for the free Licensing.biz Daily Digest and Newsflash services. You can also follow Licensing.biz on Twitter and Facebook.